Telomere-binding proteins play roles in control of replication timing
نویسندگان
چکیده
Comment on: Tazumi A, et al. Genes Dev 2012; 26:2050-62.
منابع مشابه
The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation
DNA replication in Saccharomyces cerevisiae proceeds according to a temporal program. We have investigated the role of the telomere-binding Ku complex in specifying late replication of telomere-proximal sequences. Genome-wide analysis shows that regions extending up to 80 kb from telomeres replicate abnormally early in a yku70 mutant. We find that Ku does not appear to regulate replication time...
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